DIHYDROXYACETONE ESTERS AS PRECURSORS OF TRIGLYCERIDES DURING INTESTINAL ABSORPTION

Dihydroxyacetone esters as precursors of triglycerides during intestinal absorption.

In work previously reported from this laboratory it was found that CWlabeled glycerol, completely hydrolyzed from glycerides during digestion, was not utilized for the resynthesis of lymph glycerides (1). This suggests that glycerol per se may not be the precursor of glyceride glycerol. Since absorbed fatty acids appear in the lymph as triglycerides, it is necessary to account for the origin of...

The intestinal absorption of triglycerides.

The long controversy over whether triglycerides are hydrolyzed preliminary to their absorption from the intestine may be ascribed to the difficulties in designing an experiment without alternative interpretations. In the present study it was hoped that an unequivocal experiment could be designed by labeling both the glycerol and the fatty acid moieties of ingested fat and examining the glycerid...

Fatty Acid Esterification and Chylomicron Formation during Fat Absorption. 1. Triglycerides and Cholesterol Esters.

Glyceride-Glycerol Precursors in the Intestinal Mucosa*“f

It has been shown by several workers that fatty acids liberated by the hydrolyses of their esters, such as amyl (I), ethyl (2), or the optically active mannite (3), appear in the thoracic duct chyle as triglycerides. In comparing the absorption of free palmitic acid and some of its esters, Lyman (4) found that in each case the fat deposited in the tissues was tripalmitin. It was assumed, theref...

Glyceride-Glycerol Precursors in the Intestinal Mucosa*“f

It has been shown by several workers that fatty acids liberated by the hydrolyses of their esters, such as amyl (I), ethyl (2), or the optically active mannite (3), appear in the thoracic duct chyle as triglycerides. In comparing the absorption of free palmitic acid and some of its esters, Lyman (4) found that in each case the fat deposited in the tissues was tripalmitin. It was assumed, theref...